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Hormones

Free Oestradiol Calculator

Estimate free and bioavailable oestradiol from total oestradiol, SHBG and albumin using an established mass-action equation.

pmol/L
nmol/L
g/L

Want to understand the marker?

Read what it measures and how to interpret it in context.

Estimate free oestradiol from your results

Use total oestradiol, SHBG and albumin from the same blood draw. Selected Hormone Health panels include the measurements needed for this estimate.

Key points

  • Estimates free and bioavailable oestradiol from total oestradiol, SHBG and albumin
  • Uses the mass-action method evaluated by Rinaldi and colleagues
  • Free oestradiol is unbound; bioavailable oestradiol adds the fraction loosely bound to albumin
  • Use results from the same blood draw where possible. Albumin defaults to 43 g/L when no measured value is available
  • No universal reference band is shown because oestradiol varies with sex, age, cycle stage, hormone use, assay and laboratory
  • This is a calculated estimate, not a direct measurement. A healthcare professional can interpret it in context

See your wider hormone profile

Measure total oestradiol, SHBG, albumin and the related hormones that give this estimate its clinical context.