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Hormones

Free Oestradiol Calculator

Estimate free and bioavailable oestradiol from total oestradiol, SHBG and albumin using an established mass-action equation.

pmol/L
nmol/L
g/L

Estimate free oestradiol from your results

Use total oestradiol, SHBG and albumin from the same blood draw. Selected Hormone Health panels include the measurements needed for this estimate.

Key Points

  • Estimates free and bioavailable oestradiol from total oestradiol, SHBG and albumin
  • Uses the mass-action method evaluated by Rinaldi and colleagues
  • Free oestradiol is unbound; bioavailable oestradiol adds the fraction loosely bound to albumin
  • Use results from the same blood draw where possible. Albumin defaults to 43 g/L when no measured value is available
  • No universal reference band is shown because oestradiol varies with sex, age, cycle stage, hormone use, assay and laboratory
  • This is a calculated estimate, not a direct measurement. A healthcare professional can interpret it in context

See your wider hormone profile

Measure total oestradiol, SHBG, albumin and the related hormones that give this estimate its clinical context.